Articles with "atrx lof" as a keyword



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Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma

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Published in 2020 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2020.102971

Abstract: Background In neuroblastoma, genetic alterations in ATRX, define a distinct poor outcome patient subgroup. Despite the need for new therapies, there is a lack of available models and a dearth of pre-clinical research. Methods To… read more here.

Keywords: dna damage; atrx mutant; atrx; sensitivity ... See more keywords