ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz050
Abstract: Pineal parenchymal tumors are rare neoplasms, ranging from WHO Grade I to IV. There are few studies characterizing the molecular profiles of these tumors. ATRX alterations are strongly associated with the presence of the alternative… read more here.
Keywords: atrx mutations; pineal parenchymal; parenchymal tumors; tumors intermediate ... See more keywords
ATRX histone binding and helicase activities have distinct roles in neuronal differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac683
Abstract: Abstract ATRX is a chromatin remodeler, which is mutated in ATRX syndrome, a neurodevelopmental disorder. ATRX mutations that alter histone binding or chromatin remodeling activities cluster in the PHD finger or the helicase domain respectively.… read more here.
Keywords: histone; helicase; atrx histone; atrx mutations ... See more keywords
Significance of TERT and ATRX mutations in glioma
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2018.9634
Abstract: Mutations of telomerase reverse transcriptase (TERT) and the α thalassemia/mental retardation syndrome X-linked (ATRX) genes have been the subject of numerous studies on the classification and prognosis of glioma. However, the association between TERT and… read more here.
Keywords: tert atrx; atrx mutations; tert promoter; expression ... See more keywords