Process development of [64Cu]Cu-ATSM: efficient stabilization and sterilization for therapeutic applications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-019-06738-9
Abstract: Hypoxia plays an important role in tumor prognosis. [64Cu]Cu-ATSM, a hypoxia-targeted radioactive agent, reportedly shows antitumor effect in vivo. For clinical application, [64Cu]Cu-ATSM must be manufactured at high concentrations to allow the administration of a… read more here.
Keywords: sterilization; 64cu atsm; atsm efficient; development 64cu ... See more keywords
CuII(atsm) Attenuates Neuroinflammation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00668
Abstract: Background: Neuroinflammation and biometal dyshomeostasis are key pathological features of several neurodegenerative diseases, including Alzheimer’s disease (AD). Inflammation and biometals are linked at the molecular level through regulation of metal buffering proteins such as the… read more here.
Keywords: anti inflammatory; inflammation; copper; cuii atsm ... See more keywords