The trait ‘pessimism’ does not interact with cognitive flexibility but makes rats more vulnerable to stress-induced motivational deficits: Results from the attentional set-shifting task
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.08.028
Abstract: In the present study, we have investigated the effects of the traits 'optimism' and 'pessimism' on cognitive flexibility in an animal model of depression based on chronic restraint stress. For this, first, we trained and… read more here.
Keywords: pessimism; set shifting; cognitive flexibility; stress ... See more keywords
Attentional set to safety recruits the ventral medial prefrontal cortex
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DOI: 10.1038/s41598-018-33953-3
Abstract: Early detection of danger is highly adaptive, yet fast orientation towards safety is also key to survival. This study aimed to explore how human brain searches for safety by manipulating subjects’ attentional set. Subjects were… read more here.
Keywords: safety; medial prefrontal; ventral medial; attentional set ... See more keywords
Mediodorsal Thalamus Is Critical for Updating during Extradimensional Shifts But Not Reversals in the Attentional Set-Shifting Task
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DOI: 10.1523/eneuro.0162-21.2022
Abstract: Abstract Cognitive flexibility, attributed to frontal cortex, is vital for navigating the complexities of everyday life. The mediodorsal thalamus (MD), interconnected to frontal cortex, may influence cognitive flexibility. Here, male rats performed an attentional set-shifting… read more here.
Keywords: extradimensional shifts; mediodorsal thalamus; shifting task; choice ... See more keywords