Histone H4 LRS mutations can attenuate UV mutagenesis without affecting PCNA ubiquitination or sumoylation.
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DOI: 10.1016/j.dnarep.2020.102959
Abstract: UV is a significant environmental agent that damages DNA. Translesion synthesis (TLS) is a DNA damage tolerance pathway that utilizes specialized DNA polymerases to replicate through the damaged DNA, often leading to mutagenesis. In eukaryotic… read more here.
Keywords: dna; tls; ubiquitination sumoylation; histone ... See more keywords