Intradermal co-inoculation of codon pair deoptimization (CPD)-attenuated chimeric porcine reproductive and respiratory syndrome virus (PRRSV) with Toll like receptor (TLR) agonists enhanced the protective effects in pigs against heterologous challenge.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2021.109048
Abstract: The objective of this study was to assess protective efficacy of vaccination using CPD-attenuated chimeric PRRSV and Toll like receptor (TLR) agonists (HSP70 c-terminal domain and HSPX) as adjuvants through different inoculation routes. In this… read more here.
Keywords: cpd; cpd attenuated; attenuated chimeric; tlr agonists ... See more keywords
Immunogenicity of a single fractional intradermal dose of Japanese encephalitis live attenuated chimeric vaccine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of travel medicine"
DOI: 10.1093/jtm/taac122
Abstract: BACKGROUND Japanese encephalitis (JE) is endemic in Asia and the western Pacific. Vaccination is recommended for travellers to endemic regions, but the high cost of the vaccine is a major barrier to uptake. METHODS A… read more here.
Keywords: immunogenicity; chimeric vaccine; live attenuated; attenuated chimeric ... See more keywords