Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.03.032
Abstract: Yellow fever (YF) is regarded as the original hemorrhagic fever and has been a major public health problem for at least 250years. A very effective live attenuated vaccine, strain 17D, was developed in the 1930s… read more here.
Keywords: yellow fever; attenuated vaccine; disease; fever live ... See more keywords
Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62813-8
Abstract: An effective vaccine for the hepatitis C virus (HCV) remains an unmet medical need. There is no animal model for assessing HCV vaccines; however, rodent hepacivirus (RHV) infection in laboratory rats recapitulates the lifelong chronic… read more here.
Keywords: live attenuated; infection; attenuated vaccine; hepatitis virus ... See more keywords
Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine
Sign Up to like & getrecommendations! Published in 2021 at "NPJ Vaccines"
DOI: 10.1038/s41541-021-00281-z
Abstract: Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We previously demonstrated that immunization… read more here.
Keywords: attenuated vaccine; burkholderia pseudomallei; live attenuated; vaccine ... See more keywords
Toxoplasma WH3 Δrop18 acts as a live attenuated vaccine against acute and chronic toxoplasmosis
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DOI: 10.1038/s41541-024-00996-9
Abstract: Toxoplasma gondii is a significant zoonotic pathogen of toxoplasmosis in humans and animals. Here a live attenuated Toxoplasma vaccine of WH3 Δrop18 was developed. The results showed that all mice vaccinated with WH3 Δrop18 were… read more here.
Keywords: attenuated vaccine; live attenuated; wh3; toxoplasmosis ... See more keywords
P-1419. Vaccine failure of the live-attenuated vaccine after liver transplantation depends on the vaccine strain
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.1594
Abstract: Abstract Background A recent conditional recommendation suggests considering live-attenuated vaccines for solid organ transplant recipients, yet the conditions of their safe and effective administration remain unclear. Primary vaccine failures after the first dose of live-attenuated… read more here.
Keywords: attenuated vaccine; live attenuated; vaccine; strain ... See more keywords
Construction of Heme-Binding Protein Deleted Strain and Using It as an Attenuated Vaccine Against Nocardia seriolae in Hybrid Snakehead (Channa maculata ♀ × Channa argus ♂).
Sign Up to like & getrecommendations! Published in 2025 at "Journal of fish diseases"
DOI: 10.1111/jfd.14090
Abstract: Nocardia seriolae is the main pathogen causing fish nocardiosis, which can infect various aquatic freshwater and marine fish species. We have previously confirmed that the heme-binding protein of N. seriolae (NsHBP) is a secreted protein relating… read more here.
Keywords: strain; hybrid snakehead; nocardia seriolae; attenuated vaccine ... See more keywords
Live Attenuated Vaccine Administration in Children Treated With Methotrexate or Dupilumab
Sign Up to like & getrecommendations! Published in 2024 at "Pediatric Dermatology"
DOI: 10.1111/pde.15818
Abstract: A wholesale recommendation against use of live virus vaccines in patients treated with any medication classified as an immunosuppressant has been based on global theoretical concerns rather than clinical outcomes for specific drugs. read more here.
Keywords: vaccine administration; attenuated vaccine; live attenuated; treated methotrexate ... See more keywords
Could an Unrelated Live Attenuated Vaccine Serve as a Preventive Measure To Dampen Septic Inflammation Associated with COVID-19 Infection?
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DOI: 10.1128/mbio.00907-20
Abstract: We propose the concept that administration of an unrelated live attenuated vaccine, such as MMR (measles, mumps, rubella), could serve as a preventive measure against the worst sequelae of coronavirus disease 2019 (COVID-19). There is… read more here.
Keywords: preventive measure; attenuated vaccine; unrelated live; live attenuated ... See more keywords
Development of a Bicistronic Yellow Fever Live Attenuated Vaccine with Reduced Neurovirulence and Viscerotropism
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02246-22
Abstract: Yellow fever (YF) continually spreads and causes epidemics around the world, posing a great threat to human health. The YF live attenuated vaccine 17D is considered the most efficient vaccine available and helps to successfully… read more here.
Keywords: attenuated vaccine; yellow fever; live attenuated; 17d ires ... See more keywords
Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells
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DOI: 10.1186/s12967-024-04930-4
Abstract: Glioblastoma multiforme (GBM) is the most common malignant primary brain cancer affecting the adult population. Median overall survival for GBM patients is poor (15 months), primarily due to high rates of tumour recurrence and the… read more here.
Keywords: attenuated vaccine; gbm; live attenuated; zikv lav ... See more keywords
Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Research"
DOI: 10.1186/s13567-018-0577-z
Abstract: Newcastle disease virus (NDV)-attenuated vaccine has been widely used since the 1950s and made great progress in preventing and controlling Newcastle disease. However, many reports mention exogenous virus contamination in attenuated vaccines, while co-contamination with… read more here.
Keywords: exogenous virus; attenuated vaccine; virus; newcastle disease ... See more keywords