Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.03.032
Abstract: Yellow fever (YF) is regarded as the original hemorrhagic fever and has been a major public health problem for at least 250years. A very effective live attenuated vaccine, strain 17D, was developed in the 1930s… read more here.
Keywords: yellow fever; attenuated vaccine; disease; fever live ... See more keywords
Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine
Sign Up to like & getrecommendations! Published in 2021 at "NPJ Vaccines"
DOI: 10.1038/s41541-021-00281-z
Abstract: Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We previously demonstrated that immunization… read more here.
Keywords: attenuated vaccine; burkholderia pseudomallei; live attenuated; vaccine ... See more keywords
Could an Unrelated Live Attenuated Vaccine Serve as a Preventive Measure To Dampen Septic Inflammation Associated with COVID-19 Infection?
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DOI: 10.1128/mbio.00907-20
Abstract: We propose the concept that administration of an unrelated live attenuated vaccine, such as MMR (measles, mumps, rubella), could serve as a preventive measure against the worst sequelae of coronavirus disease 2019 (COVID-19). There is… read more here.
Keywords: preventive measure; attenuated vaccine; unrelated live; live attenuated ... See more keywords
Development of a Bicistronic Yellow Fever Live Attenuated Vaccine with Reduced Neurovirulence and Viscerotropism
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02246-22
Abstract: Yellow fever (YF) continually spreads and causes epidemics around the world, posing a great threat to human health. The YF live attenuated vaccine 17D is considered the most efficient vaccine available and helps to successfully… read more here.
Keywords: attenuated vaccine; yellow fever; live attenuated; 17d ires ... See more keywords
Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Research"
DOI: 10.1186/s13567-018-0577-z
Abstract: Newcastle disease virus (NDV)-attenuated vaccine has been widely used since the 1950s and made great progress in preventing and controlling Newcastle disease. However, many reports mention exogenous virus contamination in attenuated vaccines, while co-contamination with… read more here.
Keywords: exogenous virus; attenuated vaccine; virus; newcastle disease ... See more keywords
Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007578
Abstract: Background Glanders caused by Burkholderia mallei is a re-emerging zoonotic disease affecting solipeds and humans. Furthermore, B. mallei is genetically related to B. pseudomallei, which is the causative agent of melioidosis. Both facultative intracellular bacteria… read more here.
Keywords: glanders melioidosis; attenuated vaccine; burkholderia mallei; clh001 ... See more keywords
Synergetic pathogenicity of Newcastle disease vaccines LaSota strain and contaminated chicken infectious anemia virus
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DOI: 10.3382/ps/pey555
Abstract: ABSTRACT Newcastle disease virus (NDV)‐attenuated vaccine has been widely used to prevent ND in poultry flocks, while many reports also mentioned the exogenous virus contamination in attenuated vaccines, which might be the reason for the… read more here.
Keywords: attenuated vaccine; virus; pathogenicity; ciav ... See more keywords
Visual detection and differentiation of porcine epidemic diarrhea virus wild−type strains and attenuated vaccine strains using CRISPR/Cas13a-based lateral flow strip
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.976137
Abstract: Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus that causes acute watery diarrhea and vomiting in unweaned piglets. Infections result in high mortality and serious economic losses to the swine industry. PEDV attenuated vaccine… read more here.
Keywords: attenuated vaccine; diarrhea; crispr cas13a; detection ... See more keywords
Prospects on Repurposing a Live Attenuated Vaccine for the Control of Unrelated Infections
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.877845
Abstract: Live vaccines use attenuated microbes to acquire immunity against pathogens in a safe way. As live attenuated vaccines (LAVs) still maintain infectivity, the vaccination stimulates diverse immune responses by mimicking natural infection. Induction of pathogen-specific… read more here.
Keywords: attenuated vaccine; control; live attenuated; repurposing live ... See more keywords
Recent Developments in Mycobacteria-Based Live Attenuated Vaccine Candidates for Tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112749
Abstract: Vaccination is an excellent approach to stimulating the host immune response and reducing human morbidity and mortality against microbial infections, such as tuberculosis (TB). Bacillus Calmette–Guerin (BCG) is the most widely administered vaccine in the… read more here.
Keywords: mycobacteria based; vaccine candidates; attenuated vaccine; based live ... See more keywords