GW28-e0988 Berberine attenuates cardiac fibrosis via downregulating IGF1R in diabetic rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.07.131
Abstract: Diabetic cardiac fibrosis increases ventricular stiffness and facilitates occurrence of diastolic and systolic dysfunction. IGF 1R is a key receptor regulating cell growth, survival and differentiation. However, the role of IGF 1R and its downstream… read more here.
Keywords: fibrosis; e0988 berberine; gw28 e0988; cardiac fibrosis ... See more keywords
Icariside II attenuates cardiac remodeling via AMPKα2/mTORC1 in vivo and in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2018.08.010
Abstract: Icariside II (ICA II), a flavonoid derived from Epimediumbrevicormum Maxin in, has multiple biological activities in Chinese traditional medicine. Our study aimed to investigate the potential activity of ICA II against cardiac remodeling and the… read more here.
Keywords: ampk mtorc; cardiac remodeling; ica; attenuates cardiac ... See more keywords
Valsartan attenuates cardiac dysfunction and remodelling in patients with HCM
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-021-00636-y
Abstract: Valsartan is safe and effective in improving cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from the phase II VANISH trial. read more here.
Keywords: valsartan attenuates; patients hcm; remodelling patients; cardiac dysfunction ... See more keywords
Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2020385118
Abstract: Significance Patients with rheumatoid arthritis (RA) are susceptible to heart failure accompanied by diastolic dysfunction. It is unknown what causes diastolic dysfunction in RA, and current therapies do not reduce the risk of heart problems.… read more here.
Keywords: heart; dysfunction; mice; attenuates cardiac ... See more keywords
Corrigendum to “Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis”
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/3675910
Abstract: [This corrects the article DOI: 10.1155/2016/1320365.]. read more here.
Keywords: rich saline; inflammation; corrigendum hydrogen; attenuates cardiac ... See more keywords