L6H9 attenuates LPS‐induced acute lung injury in rats through targeting MD2
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DOI: 10.1002/ddr.21607
Abstract: Acute lung injury (ALI) is a clinical syndrome characterized by respiratory failure and acute inflammatory response. Myeloid differentiation protein 2 (MD2) has been reported to play a pivotal role in the recognition of LPS and… read more here.
Keywords: md2; lps induced; acute lung; attenuates lps ... See more keywords
Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLCγ1-Ca2+-NFATc1 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-019-0289-6
Abstract: In chronic infectious diseases caused by gram-negative bacteria, such as osteomyelitis, septic arthritis, and periodontitis, osteoclastic activity is enhanced with elevated inflammation, which disturbs the bone homeostasis and results in osteolysis. Lipopolysaccharide (LPS), as a… read more here.
Keywords: lps induced; induced osteoclastogenesis; tlr4 traf6; artesunate attenuates ... See more keywords