Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1877
Abstract: AU‐rich elements (ARE) exist in the 3′‐untranslated regions of the mRNA transcribed from cell growth‐related genes such as proto‐oncogenes, cyclin‐related genes, and growth factors. HuR binds and stabilizes ARE‐mRNA. HuR is expressed abundantly in cancer… read more here.
Keywords: attenuates malignant; oral cancer; drug; cancer cells ... See more keywords
Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cell Proliferation"
DOI: 10.1111/cpr.12739
Abstract: Tanshinone I (Tan‐I) is one of the vital fatsoluble monomer components, which extracted from Chinese medicinal herb Salvia miltiorrhiza Bunge. It has been shown that Tan‐I exhibited anti‐tumour activities on different types of cancers. However,… read more here.
Keywords: apoptosis autophagy; ovarian cancer; tanshinone attenuates; attenuates malignant ... See more keywords