P0202FIRST REAL-LIFE DATA OF PATIENTS TREATED FOR THROMBOTIC THROMBOCYTOPENIC PURPURA FROM THE FRENCH THROMBOTIC MICROANGIOPATHIES NETWORK
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DOI: 10.1093/ndt/gfaa142.p0202
Abstract: Caplacizumab, a bivalent Nanobody, targets the A1 domain of von Willebrand Factor, inhibiting the interaction between ultra-large vWF and platelets in the treament of Acquired Thrombotic Thrombocytopenic Purpura (aTTP). Results of the Phase 3 HERCULES… read more here.
Keywords: attp; caplacizumab; treatment; platelet count ... See more keywords
Incidence, Diagnosis, and Outcome of Acquired Thrombotic Thrombocytopenic Purpura (aTTP): A Nationwide Survey By the Spanish Apheresis Group
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DOI: 10.1182/blood-2019-123258
Abstract: Introduction: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare disease characterized by a severe deficiency of the enzymatic activity of ADAMTS13 caused by autoantibodies, with an incidence of 3-4 x106inhabitants per year according to the… read more here.
Keywords: incidence; pex; diagnosis; treatment ... See more keywords
The Challenges in Diagnosis and Management of Acquired Thrombotic Thrombocytopenic Purpura: A Consensus Report from Three Gulf Countries
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DOI: 10.5001/omj.2022.32
Abstract: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare hematological emergency that is characterized by microangiopathic hemolytic anemia (MHA), thrombocytopenia, fever, and multiorgan failure due to autoimmune-mediated deficiency in ADAMTS-13 activity. Currently plasma exchange, with or… read more here.
Keywords: consensus; consensus report; acquired thrombotic; thrombotic thrombocytopenic ... See more keywords