Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between Substrate and Positively Charged Residues.
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DOI: 10.1021/acs.biochem.9b01005
Abstract: Gram-negative bacterial viability is greatly reduced by the disruption of heptose sugar addition during the biosynthesis of lipopolysaccharide (LPS), an important bacterial outer membrane component. Heptosyltransferase I (HepI), a member of the GT-B structural subclass… read more here.
Keywords: interactions substrate; attract escherichia; positively charged; heptosyltransferase ... See more keywords