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   Articles with "atv" as a keyword



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Physicochemical characteristics of the complexes of simvastatin and atorvastatin calcium with hydroxypropyl-β-cyclodextrin produced by mechanochemical activation

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recommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2018.05.018

Abstract: Abstract In the present work, inclusion complexes of simvastatin (SIM), atorvastatin calcium (ATV) with hydroxypropyl-β-cyclodextrin (HP-β-CD) have been prepared using mechanochemistry technique to improve solubility of the two drugs and enhance their oral bioavailability. The… read more here.

Keywords: complexes simvastatin; hydroxypropyl cyclodextrin; atv; atorvastatin calcium ... See more keywords
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Solubility enhancement of simvastatin and atorvastatin by arginine: A solvodynamics study

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recommendations! Published in 2017 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2017.05.003

Abstract: Abstract Arginine (ARG) aided solubility enhancement of statin-based model drugs such as simvastatin (SMV) and atorvastatin (ATV) has been reported. Herein, both SMV and ATV are considered as a solute, whereas ARG the cosolute. The… read more here.

Keywords: atv; arg; arginine; solubility enhancement ... See more keywords
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JA:2021-11. Exposure, Crashes, and Deaths Related to the Use of All-Terrain Vehicles for Spraying

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recommendations! Published in 2020 at "Journal of Agromedicine"

DOI: 10.1080/1059924x.2020.1763738

Abstract: ABSTRACT Purpose: All-terrain vehicles (ATVs) are valuable assets on farms and ranches, but are associated with a growing proportion of U.S. agricultural work-related deaths and injuries. The objectives of this study were to investigate the… read more here.

Keywords: related deaths; 2021 exposure; atv; private pesticide ... See more keywords
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Enhancement of the anticancer effect of atorvastatin-loaded nanoemulsions by improving oral absorption via multivalent intestinal transporter-targeting lipids

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recommendations! Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2022.2149896

Abstract: Abstract Atorvastatin (ATV) has attracted considerable attention as a potential therapeutic agent for cancer because it inhibits cancer cell proliferation by suppressing the mevalonate pathway. However, because of its low oral absorption, high doses of… read more here.

Keywords: atv; transporter; multivalent intestinal; intestinal transporter ... See more keywords
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Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines

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recommendations! Published in 2022 at "Therapeutic Drug Monitoring"

DOI: 10.1097/ftd.0000000000001043

Abstract: Supplemental Digital Content is Available in the Text. Background: Although atorvastatin (ATV) is well-tolerated, patients may report muscle complaints. These are difficult to predict owing to high interindividual variability. Such side effects are linked to… read more here.

Keywords: slco2b1 abcc1; atv; accumulation; intracellular accumulation ... See more keywords
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Specific rescue by ortho‐hydroxy atorvastatin of cortical GABAergic neurons from previous oxygen/glucose deprivation: role of pCREB

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recommendations! Published in 2017 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14210

Abstract: The statin atorvastatin (ATV) given as a post-treatment has been reported beneficial in stroke, although the mechanisms involved are not well understood so far. Here, we investigated in vitro the effect of post-treatment with ATV and… read more here.

Keywords: atv; ortho hydroxy; pcreb; post ... See more keywords
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Combined Effect of Diosgenin Along with Ezetimibe or Atorvastatin on the Fate of Labelled Bile Acid and Cholesterol in Hypercholesterolemic Rats

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recommendations! Published in 2019 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph16040627

Abstract: We analyzed the effect of diosgenin, administered with atorvastatin or ezetimibe, on the fate of 3H(G)-taurocholic acid or 26-14C-cholesterol in hypercholesterolemic rats. Male Wistar rats received a hypercholesterolemic diet (HD), HD + atorvastatin (HD+ATV), HD… read more here.

Keywords: atv; cholesterol hypercholesterolemic; effect diosgenin; diosgenin ... See more keywords