Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF-2α-Dependent Manner
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DOI: 10.3390/ijms24087031
Abstract: Autotaxin (ATX), the key enzyme that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC), is involved in tumorigenesis through the ATX-LPA axis and is regarded as a valuable target in tumor therapy. Hypoxia is a major… read more here.
Keywords: hypoxia; histone crotonylation; atx expression; expression ... See more keywords