Ataxin-3 promotes genome integrity by stabilizing Chk1
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DOI: 10.1093/nar/gkx095
Abstract: Abstract The Chk1 protein is essential for genome integrity maintenance and cell survival in eukaryotic cells. After prolonged replication stress, Chk1 can be targeted for proteasomal degradation to terminate checkpoint signaling after DNA repair finishes.… read more here.
Keywords: chk1; dna; atx3; genome integrity ... See more keywords