In utero exposure to atypical antipsychotic drug, risperidone: Effects on fetal neurotoxicity in hippocampal region and cognitive impairment in rat offspring
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2016.12.006
Abstract: ABSTRACT Clinical studies indicate that about one‐third of pregnant women with psychotic symptoms are exposed to either typical or atypical antipsychotic drugs (APDs). Reports on prenatal subject/model are lacking hence, the present study was undertaken… read more here.
Keywords: rat offspring; atypical antipsychotic; exposure; study ... See more keywords
STRUCTURE OF THE D2 DOPAMINE RECEPTOR BOUND TO THE ATYPICAL ANTIPSYCHOTIC DRUG RISPERIDONE
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/nature25758
Abstract: Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal secretion. Correspondingly, dysregulation of the dopaminergic system has been implicated in diseases such… read more here.
Keywords: atypical antipsychotic; antipsychotic drug; structure; drd2 ... See more keywords
Adverse reaction reports of neuroleptic malignant syndrome induced by atypical antipsychotic agents in the Japanese Adverse Drug Event Report (JADER) database
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12793
Abstract: This study evaluates reports on neuroleptic malignant syndrome (NMS) as an adverse event associated with the use of atypical antipsychotic agents (AAA) in Japan. We examined NMS occurrence following monotherapy and combination therapy with AAA… read more here.
Keywords: neuroleptic malignant; antipsychotic agents; atypical antipsychotic; reports neuroleptic ... See more keywords
Anodic Voltammetric Determination of an Atypical Antipsychotic Drug Amisulphide in Pharmaceutical Dosage Forms Using Electrochemical fsDNA Biosensor
Sign Up to like & getrecommendations! Published in 2019 at "Russian Journal of Electrochemistry"
DOI: 10.1134/s1023193519030042
Abstract: In this study, a new biosensor for amisulpride (ASP) determination is defined. The interaction between ASP and fish sperm double-stranded DNA (FSdsDNA) was examined by differential pulse voltammetry (DPV) method utilizing FSdsDNA modified pencil graphite… read more here.
Keywords: voltammetric determination; determination atypical; anodic voltammetric; determination ... See more keywords
Crystal Structures and Thermodynamic Properties of New Atypical Antipsychotic Cariprazine and Its Hydrochloride
Sign Up to like & getrecommendations! Published in 2018 at "Crystallography Reports"
DOI: 10.1134/s1063774518060147
Abstract: A cariprazine, an oral atypical antipsychotic acting as a D2 and D3 receptor partial agonist, has been crystallized as a free base, trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N',N'-dimethylurea, C21H32Cl2N4O (I), and as a chloride salt, trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N',N'-dimethylurea hydrochloride, C21H33Cl2N4O+Cl– (II). In… read more here.
Keywords: thermodynamic properties; structures thermodynamic; hydrochloride; atypical antipsychotic ... See more keywords
Synthesis, Preliminary Pharmacological and Acute Toxicity Studies of a New Series of 7-(2-(Benzo[d]thiazol-2-ylamino)ethoxy)-4-methyl-2H-chromen-2-one Derivatives with Atypical Antipsychotic Activity
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Pharmaceutical Sciences"
DOI: 10.36468/pharmaceutical-sciences.504
Abstract: The present study focused on the synthesis, preliminary pharmacological screening and acute toxicity testing of novel series of 7-(2-(benzo[d]thiazol-2-ylamino)ethoxy)-4-methyl-2H-chromen-2-one derivatives (4a-4k). This novel series was designated and synthesized by refluxing 2-amino benzothiazoles substituted derivatives (3a-3k)… read more here.
Keywords: atypical antipsychotic; acute toxicity; methyl chromen; preliminary pharmacological ... See more keywords
Do We Need a New Nomenclature for Atypical Antipsychotics? A Survey of Health Care Professionals and Patients.
Sign Up to like & getrecommendations! Published in 2023 at "The primary care companion for CNS disorders"
DOI: 10.4088/pcc.22m03331
Abstract: Objective: The current nomenclature for atypical antipsychotics does not indicate that they are used to treat nonpsychotic conditions (eg, bipolar disorder, major depressive disorder), which could have negative implications for both health care providers (HCPs)… read more here.
Keywords: name; class; bipolar disorder; care ... See more keywords