Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism.
Sign Up to like & getrecommendations! Published in 2021 at "Biology open"
DOI: 10.1242/bio.056457
Abstract: Genetic studies have linked FAT1 (FAT atypical cadherin 1) with autism spectrum disorder (ASD), however, the role that FAT1 plays in ASD remains unknown. In mice, the function of Fat1 has been primarily implicated in… read more here.
Keywords: atypical cadherin; autism; fat1; expression ... See more keywords
Upregulation of Atypical Cadherin FAT1 Promotes an Immunosuppressive Tumor Microenvironment via TGF-β
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DOI: 10.3389/fimmu.2022.813888
Abstract: FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic inflammatory cytokine expression in tumor cells. However, tumors also have an immunosuppressive microenvironment maintained by mediators such as transforming growth factor (TGF)-β cytokines. Here,… read more here.
Keywords: microenvironment; tumor; fat1; expression ... See more keywords