Design of stapled peptide-based PROTACs for MDM2/MDMX atypical degradation and tumor suppression
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DOI: 10.7150/thno.75444
Abstract: Rationale: Although stapled peptides offer a powerful solution to overcome the susceptibility of linear peptides to proteolytic degradation and improve their ability to cross membranes, an efficient and durable disease treatment strategy has not yet… read more here.
Keywords: peptide based; mdm2 mdmx; stapled peptide; atypical degradation ... See more keywords