Are secondary effects of bisphosphonates on the vascular system of bone contributing to increased risk for atypical femoral fractures in osteoporosis?
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DOI: 10.1002/bies.202200206
Abstract: Osteoporosis (OP) is a bone disease which affects a number of post‐menopausal females and puts many at risk for fractures. A large number of patients are taking bisphosphonates (BPs) to treat their OP and a… read more here.
Keywords: atypical femoral; increased risk; bone; secondary effects ... See more keywords
[Atypical femoral fracture : Pitfalls in surgical treatment].
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DOI: 10.1007/s00113-022-01171-2
Abstract: Atypical femoral fractures are a very rare complication after treatment with bisphosphonates. This case report describes the diagnostic criteria and some particularities of the surgical treatment. Atypical femoral fractures are typically stabilized with intramedullary nails but… read more here.
Keywords: atypical femoral; treatment; femoral fractures; pitfalls surgical ... See more keywords
Do femoral fractures in adult patients with osteogenesis imperfecta imitate atypical femoral fractures? A case series
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DOI: 10.1007/s00198-018-4769-1
Abstract: Atypical femoral fractures (AFFs) are low-energy femoral fractures with characteristic radiological features and a suspected relation to treatment with bisphosphonate (BP) or denosumab. In osteogenesis imperfecta (OI), BP is currently the drug of choice when… read more here.
Keywords: femoral fractures; treatment; bone; osteogenesis imperfecta ... See more keywords
Increased rate of reoperation in atypical femoral fractures is related to patient characteristics and not fracture type. A nationwide cohort study
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DOI: 10.1007/s00198-019-05249-3
Abstract: Summary Atypical femoral fractures are burdened with a high rate of reoperation. In our nationwide analysis, the increased rate of reoperation was related to patient background characteristics, such as age and health status, rather than… read more here.
Keywords: rate reoperation; femoral fractures; atypical femoral; reoperation ... See more keywords
Cumulative incidence of femoral localized periosteal thickening (beaking) preceding atypical femoral fractures in patients with rheumatoid arthritis
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DOI: 10.1007/s00198-020-05601-y
Abstract: Summary The incidence of localized periosteal thickening (LPT, also termed beaking) of the lateral cortex that often precedes an atypical femoral fracture (AFF) was not high in patients with rheumatoid arthritis (RA) but incomplete AFFs… read more here.
Keywords: incidence; localized periosteal; lpt; atypical femoral ... See more keywords
A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture
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DOI: 10.1007/s00223-019-00546-9
Abstract: Atypical femoral fracture is a well-documented adverse reaction to bisphosphonates. It is strongly related to duration of bisphosphonate use, and the risk declines rapidly after drug withdrawal. The mechanism behind bisphosphonate-associated atypical femoral fracture is… read more here.
Keywords: bisphosphonate associated; associated atypical; atypical femoral; femoral fracture ... See more keywords
Reliability and diagnostic utility of radiographs in patients with incomplete atypical femoral fractures
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DOI: 10.1007/s00256-019-03212-1
Abstract: ObjectiveThe aim of this study was to evaluate the sensitivity and specificity of radiographs in identifying incomplete atypical femoral fractures and to determine interobserver and intra-observer reliability.Materials and methodsAnterior–posterior and lateral radiographs of 10 femurs… read more here.
Keywords: femoral fractures; incomplete atypical; radiology; atypical femoral ... See more keywords
Intramedullary nailing of abnormally bowed atypical femoral shaft fractures: surgical technique
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DOI: 10.1007/s00402-019-03279-4
Abstract: The treatment of atypical femoral shaft fractures with abnormal bowing provides a unique challenge for surgeons. Whilst intramedullary fixation of atypical femoral shaft fractures affords both mechanical and biological benefits, the mismatch between standard intramedullary… read more here.
Keywords: shaft fractures; atypical femoral; surgical technique; femoral shaft ... See more keywords
Influence of geometry on proximal femoral shaft strains: Implications for atypical femoral fracture.
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DOI: 10.1016/j.bone.2018.02.015
Abstract: INTRODUCTION Atypical femoral fractures (AFF) are characterized as low-energy fractures of the femoral shaft or subtrochanteric region. Femoral geometry is known to play a role in AFF risk; it is hypothesized that high-risk geometries are… read more here.
Keywords: angle; femoral shaft; shaft; geometry ... See more keywords
Disturbance of osteonal bone remodeling and high tensile stresses on the lateral cortex in atypical femoral fracture after long-term treatment with Risedronate and Alfacalcidol for osteoporosis
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DOI: 10.1016/j.bonr.2021.101091
Abstract: An 83 year-old Japanese woman complained of left lateral thigh pain following a low-energy fall 4 months prior to admission. She had been treated for osteoporosis with Risedronate and Alfacalcidol for the previous five years. She was… read more here.
Keywords: lateral cortex; fracture; risedronate alfacalcidol; bone ... See more keywords
Incidence of atypical femoral fractures in the treatment of bone metastasis: An alert report
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DOI: 10.1016/j.jbo.2020.100301
Abstract: Highlights • Oncologic use of bone-modifying agents (BMAs) has been dramatically increasing.• Long-term BMA use is a risk factor for atypical femoral fracture (AFF).• We reviewed 721 patients with bone metastasis in a Japanese university… read more here.
Keywords: incidence; bone; atypical femoral; bone metastasis ... See more keywords