The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions
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DOI: 10.1007/s43440-020-00102-5
Abstract: Background The present study aimed at examining the inhibitory effect of two atypical neuroleptics iloperidone and lurasidone on the main human cytochrome P450 (CYP) enzymes in pooled human liver microsomes and cDNA-expressed CYP enzymes (supersomes).… read more here.
Keywords: human cytochrome; atypical neuroleptics; mechanism; microsomes supersomes ... See more keywords