The small molecule AU14022 promotes colorectal cancer cell death via p53‐mediated G2/M‐phase arrest and mitochondria‐mediated apoptosis
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DOI: 10.1002/jcp.26234
Abstract: The p53 tumor suppressor plays critical roles in cell cycle regulation and apoptotic cell death, with its activation capable of sensitizing cancer cells to radiotherapy or chemotherapy. To identify small molecules that induce apoptosis via… read more here.
Keywords: p53 mediated; treatment; au14022; cancer ... See more keywords