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   Articles with "auc0 auc0" as a keyword



A Randomized Phase 1 Pharmacokinetic Study Comparing the Potential Biosimilar LRG201902 With Liraglutide (Victoza®) in Healthy Male Subjects

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recommendations! Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.610880

Abstract: Objective: Pharmacokinetic (PK) similarity between biosimilar candidate LRG201902 and European Union-sourced liraglutide reference product (Victoza®) was evaluated. Safety and immunogenicity were also assessed. Methods: This single-dose, randomized, open-label, 2-period crossover study (CTR20192342) was conducted in… read more here.

Keywords: auc0 auc0; lrg201902; study; male subjects ... See more keywords

Pharmacokinetics and bioequivalence of two formulations of mifepristone tablets in healthy Chinese subjects under fasting conditions: a single-center, open, randomized, single-dose, double-period, two-sequence, crossover trial

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recommendations! Published in 2024 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2024.1479205

Abstract: Objective A bioequivalence (BE) study was performed to evaluate the pharmacokinetics, safety, and bioequivalence of two formulations of mifepristone tablets in healthy Chinese volunteers under fasting conditions. Methods A single-center, open, randomized, single-dose, double-period, two-sequence,… read more here.

Keywords: two formulations; auc0 auc0; fasting conditions; mifepristone tablets ... See more keywords

Pharmacokinetics of apixaban in patients undergoing pancreaticoduodenectomy (PAP-UP)

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recommendations! Published in 2024 at "International Journal of Clinical Pharmacology and Therapeutics"

DOI: 10.5414/cp204502

Abstract: Objective: The impact of pancreaticoduodenectomy on absorption of drugs in the duodenum remains largely unknown. We aim to characterize the pharmacokinetics of apixaban in patients who had previously undergone pancreaticoduodenectomy. Materials and methods: A single… read more here.

Keywords: auc0 inf; auc0 auc0; healthy controls; apixaban patients ... See more keywords