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Biopharmaceutical Characteristics of Nifurtimox Tablets for Age‐ and Body Weight‐Adjusted Dosing in Patients With Chagas Disease

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Published in 2020 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.871

Abstract: Treatment of Chagas disease with nifurtimox requires age‐ and body weight‐adjusted dosing, resulting in complex dosing instructions. Appropriate formulations are needed for precise and compliant dosing, especially in pediatric patients. We characterized the biopharmaceutical features… read more here.

Keywords: auc0 tlast; age body; adjusted dosing; weight adjusted ... See more keywords