869: VANCOMYCIN TROUGHS CAN PREDICT AUC/MIC RATIOS OF 400-600 IN CRITICALLY ILL PATIENTS
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000631612.17905.d2
Abstract: Introduction/Hypothesis: The efficacy of vancomycin has historically been associated with a defined trough concentration range. Accumulating evidence indicates vancomycin efficacy is more strongly associated with the achievement of a 24 hour area under the curve/minimum… read more here.
Keywords: mic ratio; 400 600; auc24 mic; trough concentration ... See more keywords
Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates
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DOI: 10.1111/bcp.13899
Abstract: Optimal dosing of vancomycin in neonates remains a matter of debate despite the frequent use of vancomycin in neonatal intensive care units (NICUs). The optimal use of vancomycin requires knowledge of its pharmacokinetics (PK) and… read more here.
Keywords: vancomycin; auc24 mic; maturational changes; dosing neonates ... See more keywords