Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission
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DOI: 10.1007/s11064-018-2700-y
Abstract: Neuroinflammation and imbalance of neurotransmitters play pivotal roles in seizures and epileptogenesis. Aucubin (AU) is an iridoid glycoside derived from Eucommia ulmoides that possesses anti-inflammatory and neuroprotective effects. However, the anti-seizure effects of AU have… read more here.
Keywords: aucubin alleviates; neuroinflammation; alleviates seizures; neurotransmission ... See more keywords
Aucubin alleviates diabetic nephropathy by inhibiting NF-κB activation and inducing SIRT1/SIRT3-FOXO3a signaling pathway in high-fat diet/streptozotocin-induced diabetic mice
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DOI: 10.1016/j.jff.2019.103702
Abstract: Abstract Oxidative stress and inflammation are two important pathological mechanisms in diabetic nephropathy (DN). Aucubin (AU), a natural iridoid glucoside, possessing remarkable anti-inflammatory and anti-oxidation activity, has been used to treat diabetic complications. However, underlying… read more here.
Keywords: aucubin alleviates; signaling pathway; sirt1 sirt3; diabetic nephropathy ... See more keywords