Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model
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DOI: 10.1007/s11060-018-2894-5
Abstract: BackgroundGlioblastoma multiforme (GBM) is the most malignant of brain tumors. Acquired drug resistance is a major obstacle for successful treatment. Earlier studies reported that expression of the multiple drug resistance gene (MDR1) is regulated by… read more here.
Keywords: akt; augments anti; dkk3; anti tumor ... See more keywords