Omecamtiv mecarbil augments cardiomyocyte contractile activity both at resting and systolic Ca2+ levels
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DOI: 10.1002/ehf2.14300
Abstract: Heart failure with reduced ejection fraction (HFrEF) is a disease with high mortality and morbidity. Recent positive inotropic drug developments focused on cardiac myofilaments, that is, direct activators of the myosin molecule and Ca2+ sensitizers… read more here.
Keywords: omecamtiv mecarbil; cardiomyocyte contractile; mecarbil augments; augments cardiomyocyte ... See more keywords