Role of the Enzymatic Environment in the Reactivity of the AuIII-C^N^C Anticancer Complexes.
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DOI: 10.1021/acs.inorgchem.0c03521
Abstract: The action mechanism of anticancer gold(III) complexes is a multi-step process and depends on their redox stability. First, the gold(III) complex undergoes a ligand exchange reaction in the presence of cellular thiols, such as those… read more here.
Keywords: role enzymatic; auiii; enzyme structure; enzyme ... See more keywords
Comparing Metal–Halide and −Oxygen Adducts in Oxidative C/O–H Activation: AuIII–Cl versus AuIII–OH
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DOI: 10.1021/acs.inorgchem.1c02222
Abstract: High-valent metal–halides have come to prominence as highly effective oxidants. A direct comparison of their efficacy against that of traditional metal–oxygen adducts is needed. [AuIII(Cl)(terpy)](ClO4)2 (1; terpy = 2,2′:6′,2-terpyridine) readily oxidized substrates bearing O–H and… read more here.
Keywords: oxygen; metal halide; auiii; comparing metal ... See more keywords
Stable AuIII complexes with four N-heterocyclic carbene groups can be prepared in high yield directly from KAuCl4.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt01272a
Abstract: Gold(iii) N-heterocyclic carbene (NHC) complexes of form [Au(NHC)4Cl2]Cl were synthesized by reaction of KAuCl4 with bis- and tetrakis(imidazolium) salts in the presence of a mild base. Treatment of these complexes with KPF6 afforded four-coordinate AuIII… read more here.
Keywords: auiii nhc; auiii; auiii complexes; nhc 4cl2 ... See more keywords