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   Articles with "auraptene" as a keyword



Safety evaluation of auraptene in rats in acute and subacute toxicity studies

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recommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"

DOI: 10.1016/j.yrtph.2017.10.025

Abstract: ABSTRACT Auraptene (AUR) is a natural, bioactive, monoterpene coumarin ether. It has anti‐inflammatory, anti‐carcinogenic, anti‐bacterial, neuroprotective, and hepatoprotective properties. The aim of the present study was to assess the acute and subacute toxicity of oral… read more here.

Keywords: administration aur; acute subacute; auraptene; toxicity ... See more keywords

Joining up the scattered anticancer knowledge on auraptene and umbelliprenin: a meta-analysis

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-62747-z

Abstract: Auraptene (AUR) and umbelliprenin (UMB) are naturally occurring prenylated coumarins that have demonstrated promising anticancer effects across various human cancer cell lines. This meta-analysis aimed to systematically assess, compare, and quantify the anticancer efficacy of… read more here.

Keywords: anticancer; auraptene; meta analysis; aur umb ... See more keywords

Comparing toxicity of galbanic acid, auraptene and umbelliprenin on adult T-cell leukaemia-lymphoma in normoxia and hypoxia.

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recommendations! Published in 2022 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2022.68.12.4

Abstract: Natural coumarins are valuable agents that induce anticancer effects and/or enhance sensitivity to therapeutic modalities. Galbanic acid (GBA), auraptene (AUR) and umbelliprenin (UMB) are coumarins derived from Ferula species with various pharmaceutical activities. The aim… read more here.

Keywords: lymphoma; normoxia hypoxia; galbanic acid; toxicity ... See more keywords

A Review of Auraptene as an Anticancer Agent

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recommendations! Published in 2021 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.698352

Abstract: Auraptene is a bioactive monoterpene coumarin isolated from Citrus aurantium and Aegle marmelos that belong to the Rutaceae family. Auraptene can modulate intracellular signaling pathways that control cell growth, inflammation and apoptosis and can exert… read more here.

Keywords: anticancer agent; auraptene; auraptene anticancer; review auraptene ... See more keywords

Natural Product Auraptene Targets SLC7A11 for Degradation and Induces Hepatocellular Carcinoma Ferroptosis

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recommendations! Published in 2024 at "Antioxidants"

DOI: 10.3390/antiox13081015

Abstract: The natural product auraptene can influence tumor cell proliferation and invasion, but its effect on hepatocellular carcinoma (HCC) cells is unknown. Here, we report that auraptene can exert anti-tumor effects in HCC cells via inhibition… read more here.

Keywords: natural product; auraptene; ferroptosis; product auraptene ... See more keywords