Enhancement of photodynamic inactivation of Staphylococcus aureus biofilms by disruptive strategies
Sign Up to like & getrecommendations! Published in 2017 at "Lasers in Medical Science"
DOI: 10.1007/s10103-017-2253-3
Abstract: Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers and visible light. On the one hand, near-infrared treatment (NIRT) has also bactericidal and dispersal effects on biofilms. In addition, dispersal… read more here.
Keywords: staphylococcus aureus; aureus biofilms; microscopy; photodynamic inactivation ... See more keywords
Microrheology and Spatial Heterogeneity of Staphylococcus aureus Biofilms Modulated by Hydrodynamic Shear and Biofilm-Degrading Enzymes
Sign Up to like & getrecommendations! Published in 2019 at "Langmuir"
DOI: 10.1021/acs.langmuir.8b04252
Abstract: Particle tracking microrheology was used to investigate the viscoelasticity of Staphylococcus aureus biofilms grown in microfluidic cells at various flow rates and when subjected to biofilm-degrading enzymes. Biofilm viscoelasticity was found to harden as a… read more here.
Keywords: staphylococcus aureus; biofilm degrading; modulated hydrodynamic; degrading enzymes ... See more keywords
MoS2@polydopamine-Ag nanosheets with enhanced antibacterial activity for effective treatment of Staphylococcus aureus biofilms and wound infection.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr04111c
Abstract: Developing novel antibacterial agents to combat bacterial infection has been an everlasting task for scientists, due to the drug resistance evolved by bacteria during antibiotic treatment. In this work, we used polydopamine (PDA) to modify… read more here.
Keywords: staphylococcus aureus; mpa nss; treatment; aureus ... See more keywords
Novel anti‐staphylococcal and anti‐biofilm properties of two anti‐malarial compounds: MMV665953 {1‐(3‐chloro‐4‐fluorophenyl)‐3‐(3,4‐dichlorophenyl)urea} and MMV665807 {5‐chloro‐2‐hydroxy‐N‐[3‐(trifluoromethyl)phenyl]benzamide}
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000446
Abstract: Purpose. The treatment of device‐related infections is challenging and current anti‐microbial compounds have poor anti‐biofilm activity. We aimed to identify and characterize novel compounds effective in the eradication of Staphylococcus aureus biofilms. Methodology. Two novel… read more here.
Keywords: aureus biofilms; anti biofilm; biofilm; mmv665807 ... See more keywords
Synthesis of benzoylthiourea derivatives and analysis of their antibacterial performance against planktonic Staphylococcus aureus and its biofilms
Sign Up to like & getrecommendations! Published in 2020 at "Letters in Applied Microbiology"
DOI: 10.1111/lam.13359
Abstract: Following the appearance of several antimicrobial agents to control the spread of infections, two major challenges have emerged: (i) the occurrence and blowout of multiresistant bacteria and the increase of chronic diseases and (ii) difficult‐to‐eradicate… read more here.
Keywords: staphylococcus aureus; microscopy; benzoylthiourea derivatives; formation ... See more keywords
Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02073-19
Abstract: Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S. aureus UAMS-1 biofilms with HT61, a quinoline derivative… read more here.
Keywords: aureus biofilms; quinoline derivative; staphylococcus; ht61 ... See more keywords
Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02666-16
Abstract: ABSTRACT Biofilms pose a unique therapeutic challenge because of the antibiotic tolerance of constituent bacteria. Treatments for biofilm-based infections represent a major unmet medical need, requiring novel agents to eradicate mature biofilms. Our objective was… read more here.
Keywords: agent; bacteriophage lysin; lysin 301; biofilm ... See more keywords
Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases
Sign Up to like & getrecommendations! Published in 2023 at "mBio"
DOI: 10.1128/mbio.00587-23
Abstract: ABSTRACT Phenol-soluble modulins (PSMs) are the primary proteinaceous component of Staphylococcus aureus biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can lead to persistent infections… read more here.
Keywords: psm peptides; system; aureus biofilms; staphylococcus aureus ... See more keywords
Evaluation of the antibacterial activity of gallic acid anchored phthalocyanine-doped silica nanoparticles towards Escherichia coli and Staphylococcus aureus biofilms and planktonic cells.
Sign Up to like & getrecommendations! Published in 2023 at "Photodiagnosis and photodynamic therapy"
DOI: 10.2139/ssrn.4356122
Abstract: In this work, we have described the synthesis of phthalocyanine complexes Zn(II) tetrakis 4-(5-formylpyridin-2-yl)oxy) phthalocyanine (2), Zn(II) tetrakis-1-butyl-4-(2-(6- (tetra-phenoxy)pyridin-3-yl) vinyl)pyridin-1-ium phthalocyanine (3) and Zn(II) tetrakis 1-butyl-5-(2-(1-butylpyridin-1-ium-4-yl)vinyl)-2-(tetra-phenoxy)pyridin-1-ium phthalocyanine (4). The effect of a varying number of… read more here.
Keywords: silica nanoparticles; gallic acid; aureus biofilms; phthalocyanine ... See more keywords
Evaluation of Staphylococcal Bacteriophage Sb-1 as an Adjunctive Agent to Antibiotics Against Rifampin-Resistant Staphylococcus aureus Biofilms
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.602057
Abstract: Rifampin plays a crucial role in the treatment of staphylococcal implant-associated infection, as it is the only antibiotic capable of eradicating Staphylococcus aureus biofilms. However, the emergence of rifampin resistance strongly limits its use. Combinatorial… read more here.
Keywords: staphylococcus aureus; aureus; aureus biofilms; rifampin resistant ... See more keywords
Microbial Metabolic Genes Crucial for S. aureus Biofilms: An Insight From Re-analysis of Publicly Available Microarray Datasets
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.607002
Abstract: Bacterial biofilms are microbial lifestyles found in all environments. Up to 80% of human infections and 60–70% of hospital-acquired infections have a biofilm origin, with Staphylococcus aureus one of the leading causes of these infections.… read more here.
Keywords: publicly available; analysis; aureus; biofilm ... See more keywords