L-Threoascorbic acid treatment promotes S. aureus-infected primary human endothelial cells survival and function, as well as intracellular bacterial killing, and immunomodulates the release of IL-1β and soluble ICAM-1.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107476
Abstract: BACKGROUND Vitamin C (ascorbic acid, AscH2) has been shown to enhance immunity. Here, we studied its immunomodulatory effect on human endothelial cells (ECs) during S. aureus infection. MATERIALS AND METHODS The ex vivo effects of… read more here.
Keywords: asch2 treatment; treatment; huvecs; endothelial cells ... See more keywords
Superstretchable and Tough Physical Cross-Linking Hydrogels with Dual pH and Temperature Responsiveness for In Vivo Treatment of Staphylococcus aureus-Infected Wounds.
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DOI: 10.1021/acs.biomac.5c01367
Abstract: Developing a single hydrogel with comprehensive wound healing functions is challenging. We developed a composite hydrogel wound dressing with thermal and pH responsiveness, demonstrating antibacterial and biocompatible properties in rats with Staphylococcus aureus-infected wounds. Sodium… read more here.
Keywords: temperature; infected wounds; aureus infected; staphylococcus aureus ... See more keywords
LC-MS/MS metabolomics profiling of Glechoma hederacea L. methanolic extract; in vitro antimicrobial and in vivo with in silico wound healing studies on Staphylococcus aureus infected rat skin wound
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DOI: 10.1080/14786419.2022.2108421
Abstract: Abstract LC-MS/MS analysis of Glechoma hederacea L. methanolic extract (GHME), revealed the identification of 25 metabolites. Ursolic acid (1), 2α-hydroxyursolic acid or corosolic acid (2), 2β-hydroxyursolic acid or epi-corosolic (3), luteolin 7-O-β-D-glucopyranoside (4) and rosmarinic… read more here.
Keywords: wound healing; methanolic extract; glechoma hederacea; staphylococcus aureus ... See more keywords