Bacterial Toxin‐Triggered Release of Antibiotics from Capsosomes Protects a Fly Model from Lethal Methicillin‐Resistant Staphylococcus aureus (MRSA) Infection
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DOI: 10.1002/adhm.202200036
Abstract: Antibiotic resistance is a severe global health threat and hence demands rapid action to develop novel therapies, including microscale drug delivery systems. Herein, a hierarchical microparticle system is developed to achieve bacteria‐activated single‐ and dual‐antibiotic… read more here.
Keywords: methicillin resistant; staphylococcus aureus; aureus mrsa; mrsa infection ... See more keywords
Identification of botanicals with potential therapeutic use against methicillin‐resistant Staphylococcus aureus (MRSA) infections
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DOI: 10.1002/ptr.6198
Abstract: Staphylococcus aureus is an opportunistic pathogen. Over‐ and improper‐use of pharmaceuticals against S. aureus has led to the development of antibiotic resistance, including methicillin‐resistant S. aureus (MRSA). This study examined the efficacy of botanical extracts… read more here.
Keywords: methicillin resistant; aureus; staphylococcus aureus; aureus mrsa ... See more keywords
The antibacterial activity of LI-F type peptide against methicillin-resistant Staphylococcus aureus (MRSA) in vitro and inhibition of infections in murine scalded epidermis
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DOI: 10.1007/s00253-017-8669-7
Abstract: LI-F type peptides are a family of cyclic lipodepsipeptide antibiotics isolated from Paenibacillus polymyxa and display potent activities against positive bacteria including methicillin-resistant S. aureus (MRSA). In this study, we investigated the mechanism of action… read more here.
Keywords: type; amp jsa9; methicillin resistant; aureus mrsa ... See more keywords
Isolation, Identification, and Characterization of a Novel Bacteriocin Produced by Brevibacillus laterosporus DS-3 Against Methicillin-Resistant Staphylococcus aureus (MRSA)
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DOI: 10.1007/s10989-019-09878-4
Abstract: Isolation and characterization of a bacteriocin from Brevibacillus laterosporus DS-3 and its ability in producing antibacterial activity were examined in this study. We isolated 48 bacterial strains from different native ecological niches. Sources included lake… read more here.
Keywords: staphylococcus aureus; bacteriocin; aureus mrsa; resistant staphylococcus ... See more keywords
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
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DOI: 10.1016/j.ejmech.2016.12.060
Abstract: Diaryltriazene derivatives were synthesized and evaluated for their antimicrobial properties. Initial experiments showed some of these compounds to have activity against both methicillin-resistant strains of Staphylococus aureus (MRSA) and Mycobacterium smegmatis, with MICs of 0.02… read more here.
Keywords: aureus mrsa; methicillin resistant; mrsa; mrsa mycobacterium ... See more keywords
Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.11.012
Abstract: The multidrug-resistant Staphylococcus aureus (MRSA) is one of the most prevalent human pathogens involved in many minor to major disease burdens throughout the world. Inhibition of biofilm formation is an attractive strategy to treat diseases… read more here.
Keywords: staphylococcus aureus; resistant staphylococcus; aureus mrsa;
Design, synthesis and in vivo evaluation of 3-arylcoumarin derivatives of rhenium(I) tricarbonyl complexes as potent antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA).
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DOI: 10.1016/j.ejmech.2020.112533
Abstract: We have prepared a series of ten 3-arylcoumarin molecules, their respective fac-[Re(CO)3(bpy)L]+ and fac-[Re(CO)3(L⁀L)Br] complexes and tested all compounds for their antimicrobial efficacy. Whereas the 3-arylcoumarin ligands are virtually inactive against the human-associated pathogens with… read more here.
Keywords: staphylococcus aureus; vivo; aureus mrsa; methicillin resistant ... See more keywords
Antioxidant-based synergistic eradication of methicillin-resistant Staphylococcus aureus (MRSA) biofilms with bacitracin.
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DOI: 10.1016/j.ijantimicag.2018.03.006
Abstract: Biofilms of methicillin-resistant Staphylococcus aureus (MRSA) have serious clinical implications. However, it is difficult to eradicate MRSA biofilms due to the increased tolerance to antimicrobials of biofilms. In this study, we investigated the synergistic anti-biofilm… read more here.
Keywords: staphylococcus aureus; aureus mrsa; resistant staphylococcus; methicillin resistant ... See more keywords
Methicillin-resistant Staphylococcus aureus (MRSA) in Iran: A systematic review and meta-analysis.
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DOI: 10.1016/j.jgar.2017.09.006
Abstract: INTRODUCTION Methicillin-resistant Staphylococcus aureus (MRSA) is among the most prevalent pathogens causing healthcare-associated infections. Accurate and updated data describing the epidemiology of MRSA are crucial for the development of national policies to control MRSA infection… read more here.
Keywords: staphylococcus aureus; analysis; aureus mrsa; resistant staphylococcus ... See more keywords
Remarkable capacity of brosimine b to disrupt methicillin-resistant Staphylococcus aureus (MRSA) preformed biofilms.
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DOI: 10.1016/j.micpath.2020.103967
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health concern representing about 60% of S. aureus isolated from hospitalized patients in countries such as USA and Brazil in the last years. Additionally, the ability to… read more here.
Keywords: methicillin; staphylococcus aureus; aureus; aureus mrsa ... See more keywords
Development of Aromatic-Linked Diamino Acid Antimicrobial Peptide Mimics with Low Hemolytic Toxicity and Excellent Activity against Methicillin-Resistant Staphylococcus aureus (MRSA).
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DOI: 10.1021/acs.jmedchem.2c01583
Abstract: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become one of the biggest threats to public health. To develop new antibacterial agents against MRSA, a series of diamino acid compounds with aromatic nuclei linkers were… read more here.
Keywords: methicillin resistant; staphylococcus aureus; aureus; aureus mrsa ... See more keywords