Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41826-6
Abstract: Staphylococcus aureus pneumonia is associated with high mortality irrespective of antibiotic susceptibility. Both MRSA and MSSA strains produce powerful cytotoxins: alpha-hemolysin(Hla) and up to five leukocidins – LukSF-PV, HlgAB, HlgCB, LukED and LukGH (LukAB) –… read more here.
Keywords: pneumonia models; pathology; aureus pneumonia; rabbit ... See more keywords
Mast cells participate in regulation of lung‐gut axis during Staphylococcus aureus pneumonia
Sign Up to like & getrecommendations! Published in 2019 at "Cell Proliferation"
DOI: 10.1111/cpr.12565
Abstract: The lung‐gut axis is known to be involved in the pathogenesis of Staphylococcus aureus pneumonia. However, the underlying mechanisms remain unclear. We examined the role of pulmonary mast cells (MCs) in the regulation of the… read more here.
Keywords: lung gut; aureus pneumonia; gut axis;
Exploring Virulence Factors and Alternative Therapies against Staphylococcus aureus Pneumonia
Sign Up to like & getrecommendations! Published in 2020 at "Toxins"
DOI: 10.3390/toxins12110721
Abstract: Pneumonia is an acute pulmonary infection associated with high mortality and an immense financial burden on healthcare systems. Staphylococcus aureus is an opportunistic pathogen capable of inducing S. aureus pneumonia (SAP), with some lineages also… read more here.
Keywords: exploring virulence; staphylococcus aureus; virulence factors; aureus pneumonia ... See more keywords