Articles with "aureus topoisomerase" as a keyword



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Thiosemicarbazide Derivatives Decrease the ATPase Activity of Staphylococcus aureus Topoisomerase IV, Inhibit Mycobacterial Growth, and Affect Replication in Mycobacterium smegmatis

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22083881

Abstract: Compounds targeting bacterial topoisomerases are of interest for the development of antibacterial agents. Our previous studies culminated in the synthesis and characterization of small-molecular weight thiosemicarbazides as the initial prototypes of a novel class of… read more here.

Keywords: staphylococcus aureus; topoisomerase; activity staphylococcus; aureus topoisomerase ... See more keywords