Articles with "aurkb" as a keyword



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The Regulation of let-7c-5p on the Biological Characteristics of Lung Adenocarcinoma Cells by Targeting AURKB

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Published in 2022 at "Molecular Biotechnology"

DOI: 10.1007/s12033-021-00446-0

Abstract: To study the modulatory mechanism of let-7c-5p on the biological characteristics of lung adenocarcinoma (LUAD) cells by targeting AURKB. Differentially expressed genes (DEGs) were screened by bioinformatics analysis. CCK-8, colony formation, scratch healing, Transwell, and… read more here.

Keywords: characteristics lung; aurkb; luad cells; biological characteristics ... See more keywords
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Role of aurora kinase B in regulating resistance to paclitaxel in breast cancer cells

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Published in 2022 at "Human Cell"

DOI: 10.1007/s13577-022-00675-8

Abstract: Aurora kinase B (AURKB) is a type of functional kinase with primary functions of participating in cell mitosis, which has been identified to be involved in the occurrence and development of malignant tumors strongly. However,… read more here.

Keywords: cancer cells; aurkb; drug; breast cancer ... See more keywords
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BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB

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Published in 2021 at "eLife"

DOI: 10.7554/elife.70385

Abstract: Benign melanocytic nevi frequently emerge when an acquired BRAFV600E mutation triggers unchecked proliferation and subsequent arrest in melanocytes. Recent observations have challenged the role of oncogene-induced senescence in melanocytic nevus formation, necessitating investigations into alternative… read more here.

Keywords: aurkb; brafv600e induces; human melanocytes; proliferation ... See more keywords