Abstract 708: Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer (TNBC)
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DOI: 10.1158/1538-7445.am2024-708
Abstract: Purpose: Triple negative breast cancer (TNBC) is an aggressive breast cancer (BC) subtype with few treatment options. Radiation therapy (RT) is a mainstay therapy for the treatment of BC, but local recurrence following RT therapy… read more here.
Keywords: cancer; aurkb inhibition; syngeneic; triple negative ... See more keywords
Abstract 1829: Potentiating antitumoral type 1 interferon immune signaling in triple-negative breast cancer (TNBC) via combination treatment of Aurora kinase B (AURKB) inhibition and radiation therapy
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DOI: 10.1158/1538-7445.am2025-1829
Abstract: Triple-negative breast cancer (TNBC) is an aggressive BC subset that is less responsive to standard therapies resulting in the need for novel treatment options. Radiotherapy (RT) is common for treating TNBC patients; however, locoregional recurrence… read more here.
Keywords: cancer; treatment; aurkb inhibition; tnbc ... See more keywords