Cadherin-2 mediates spatiotemporal control of actomyosin contractility during zippering and neural tube closure in a simple chordate
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.254
Abstract: morphogenesis coupled to cell proliferation. Coordination of cell shape changes and cell divisions requires spatially-biased remodelling of actomyosin cytoskeleton in response to intrinsic or extrinsic inputs. In Caenorhabditis elegans zygotes, transient flows of cortical actomyosin… read more here.
Keywords: cell; actomyosin; cadherin mediates; actomyosin contractility ... See more keywords
Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase
Sign Up to like & getrecommendations! Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2016.49
Abstract: Aurora-A kinase functions mainly in centrosome maturation, separation and spindle formation. It has also been found to be amplified or overexpressed in a range of solid tumors, which is linked with tumor progression and poor… read more here.
Keywords: spindle; checkpoint; haspin; late phase ... See more keywords
Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e23-01-0014
Abstract: Proper chromosome segregation depends on establishment of bioriented kinetochore-microtubule attachments, which often requires multiple rounds of release and reattachment. Aurora B and C kinases phosphorylate kinetochore proteins to release tensionless attachments. Multiple pathways recruit Aurora… read more here.
Keywords: aurora; kinetochore; chromosome segregation; centromere kinetochore ... See more keywords
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041936
Abstract: Aurora kinases are serine/threonine kinases required for cell proliferation and are overexpressed in many human cancers. Targeting Aurora kinases has been a therapeutic strategy in cancer treatment. Here, we attempted to identify a deubiquitinase (DUB)… read more here.
Keywords: deubiquitinase; kinase; otud6a aurora; aurora kinase ... See more keywords