Large-Scale Reprogramming and Neuronal Differentiation In Complex Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.06.124
Abstract: Abstract Psychiatric disorders are etiologically heterogeneous and complex. For example, it has been demonstrated that hundreds of genetic loci contribute to risk for autism or schizophrenia. These loci include rare variation of major effect as… read more here.
Keywords: common variation; psychiatric disorders; risk; autism schizophrenia ... See more keywords
Neurexins in autism and schizophrenia—a review of patient mutations, mouse models and potential future directions
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-00944-8
Abstract: Mutations in the family of neurexins (NRXN1, NRXN2 and NRXN3) have been repeatedly identified in patients with autism spectrum disorder (ASD) and schizophrenia (SCZ). However, it remains unclear how these DNA variants affect neurexin functions… read more here.
Keywords: mouse models; lof; schizophrenia review; neurexins autism ... See more keywords
Overestimation of volatility in schizophrenia and autism? A comparative study using a probabilistic reasoning task
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DOI: 10.1371/journal.pone.0244975
Abstract: Background and objectives A plethora of studies has investigated and compared social cognition in autism and schizophrenia ever since both conditions were first described in conjunction more than a century ago. Recent computational theories have… read more here.
Keywords: task; autism; study; overestimation volatility ... See more keywords