Neuropsychological correlates of cognitive, emotional-affective and auto-activation apathy in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychologia"
DOI: 10.1016/j.neuropsychologia.2018.01.039
Abstract: Abstract Apathy symptoms include different dimensions: cognitive (C), emotional‐affective (E‐Aff) and auto‐activation; they have been related to dysfunctions of the dorsolateral, orbito‐basal prefrontal cortex and the subcortical frontal connections to the basal ganglia, respectively. In… read more here.
Keywords: auto; emotional affective; activation apathy; association ... See more keywords
p38α Kinase Auto-Activation through Its Conformational Transition Induced by Tyr323 Phosphorylation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c00236
Abstract: p38α is a key serine/threonine kinase that can enable atypical auto-activation through Zap70 phosphorylation and initiate T cell receptor signaling. The auto-activation plays an important role in autoimmune diseases. Although the classical activation mechanism of… read more here.
Keywords: conformational transition; auto activation; phosphorylation; p38 ... See more keywords