Complement deposition induced by binding of anti-contactin-1 auto-antibodies is modified by immunoglobulins
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2016.10.006
Abstract: &NA; Inflammatory neuropathies associated with auto‐antibodies against paranodal proteins like contactin‐1 are reported to respond poorly to treatment with intravenous immunoglobulins (IVIG). A reason might be that IVIG interacts with the complement pathway and these… read more here.
Keywords: auto; complement deposition; auto antibodies; anti contactin ... See more keywords
Proteomics characterization of CENP-B epitope in Moroccan scleroderma patients with anti-centromere autoantibodies.
Sign Up to like & getrecommendations! Published in 2020 at "Immunology letters"
DOI: 10.1016/j.imlet.2020.02.005
Abstract: BACKGROUND Anti-centromere auto-antibodies (ACA) have been described as a marker in Systemic sclerosis (SSc) disease. CENP-B is the major centromere auto-antigen recognized by SSc patients with positive ACA. Our aim was to characterize the major… read more here.
Keywords: ssc; auto antibodies; epitope moroccan; epitope ... See more keywords
Heterogeneity of auto-antibodies against nAChR in myasthenic serum and their pathogenic roles in experimental autoimmune myasthenia gravis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2018.04.014
Abstract: Many myasthenia gravis (MG) patients have auto-antibodies against the nicotinic acetylcholine receptor (nAChR), and monoclonal antibodies against the main immunogenic region (MIR) of nAChR can induce experimental autoimmune MG (EAMG). We investigated whether Fab fragment… read more here.
Keywords: eamg serum; serum; myasthenia gravis; auto antibodies ... See more keywords
146. Regulatory (auto-) antibodies against G-coupled receptors in women ten years after early-onset preeclampsia: Results from the PREVFEM study
Sign Up to like & getrecommendations! Published in 2018 at "Pregnancy Hypertension"
DOI: 10.1016/j.preghy.2018.08.251
Abstract: Introduction Preeclampsia (PE) is associated with an increased cardiovascular risk in later life, especially in women after early-onset PE. We and others have shown that activating antibodies against angiotensin II receptor type 1 (AT1-) are… read more here.
Keywords: early onset; regulatory auto; antibodies coupled; coupled receptors ... See more keywords
Zika virus infection elicits auto-antibodies to C1q
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20185-8
Abstract: Zika virus (ZIKV) causes mostly asymptomatic infection or mild febrile illness. However, with an increasing number of patients, various clinical features such as microcephaly, Guillain-Barré syndrome and thrombocytopenia have also been reported. To determine which… read more here.
Keywords: infection elicits; infection; elicits auto; zika virus ... See more keywords
Anti-pentraxin 3 auto-antibodies might be protective in lupus nephritis: a large cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Renal Failure"
DOI: 10.1080/0886022x.2017.1308258
Abstract: Abstract Objectives: Anti-pentraxin 3 (PTX3) auto-antibodies were found to be associated with the absence of renal involvement in systemic lupus erythematosus (SLE). This study is to investigate the prevalence of anti-PTX3 auto-antibodies and their clinical… read more here.
Keywords: auto; ptx3 auto; lupus nephritis; anti ptx3 ... See more keywords
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2018 at "mAbs"
DOI: 10.1080/19420862.2018.1494107
Abstract: ABSTRACT Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor that can stimulate a variety of cells, but its overexpression leads to excessive production and activation of granulocytes and macrophages with many pathogenic effects. This… read more here.
Keywords: auto; human csf; csf auto; mechanism csf ... See more keywords
Clinical correlations with disease-associated auto-antibodies in a Chinese cohort with systemic sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001935
Abstract: To the Editor: Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive skin and visceral fi brosis, microvasculopathy, and autoimmunity. Circulat-ing auto-antibodies (AAbs) are detectable in 90% to 95% of patients with SSc. [1]… read more here.
Keywords: auto antibodies; systemic sclerosis; associated auto; auto ... See more keywords
Cutaneous‐type pemphigus vulgaris might be a transient subtype in pemphigus vulgaris: a case series
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18348
Abstract: Dear Editor Pemphigus vulgaris (PV) is an autoimmune blistering disease involving mainly the mucous membrane with or without cutaneous erosions. In recent years, there have been emerging discussions among the cutaneous-type PV (cPV), which was… read more here.
Keywords: dsg3; auto antibodies; pemphigus vulgaris; auto ... See more keywords
FRI0437 Is extended auto antibody profiling associated with the prevalence of disease complications?
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.3496
Abstract: Background Auto antibodies play a prominent role in both classification and disease prognosis of systemic sclerosis (SSc). In several cohorts the association between auto antibodies and prognostic factors has been described. In recent years, new… read more here.
Keywords: auto; antibody; disease; prevalence ... See more keywords