Idarubicin plus BuCy versus BuCy conditioning regimens for intermediate‐risk acute myeloid leukemia in first complete remission undergoing auto‐HSCT: An open‐label, multicenter, randomized phase 3 trial
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26800
Abstract: We report a randomized prospective phase 3 study, designed to evaluate the efficacy and tolerability of idarubicin plus busulfan and cyclophosphamide (IDA‐BuCy) versus BuCy in autologous hematopoietic stem‐cell transplantation (auto‐HSCT) for intermediate‐risk acute myeloid leukemia… read more here.
Keywords: ida bucy; bucy; auto hsct;
Induction with MEDA regimen and consolidation with Auto‐HSCT for stage IV NKTCL patients: A prospective multicenter study
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DOI: 10.1002/ijc.34055
Abstract: Optimal treatment strategies for natural killer/T‐cell lymphoma (NKTCL) patients with stage IV disease have not been well defined. In this prospective phase 2 study, we evaluated the treatment using MEDA (methotrexate, etoposide, dexamethasone and pegaspargase)… read more here.
Keywords: auto; auto hsct; nktcl patients; rate ... See more keywords
Immunogenicity of Inactivated Varicella Zoster Vaccine (ZVIN) in Autologous Hematopoietic Stem Cell Transplant (auto-HSCT) Recipients
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DOI: 10.1093/ofid/ofx162.141
Abstract: Abstract Background Recipients of auto-HSCT have an increased risk of herpes zoster (HZ) infection; however, live attenuated varicella-zoster virus (VZV) vaccine is contraindicated in these patients. In this pivotal Phase III study (V212-001; NCT01229267) inactivated… read more here.
Keywords: merck; vaccine; auto hsct; placebo ... See more keywords
A multicenter retrospective study on the real-world outcomes of autologous vs. allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphoma in China
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DOI: 10.1097/cm9.0000000000001575
Abstract: Supplemental Digital Content is available in the text Abstract Background: There were few studies on real-world data about autologous hematopoietic stem cell transplantation (auto-HSCT) or allogeneic HSCT (allo-HSCT) in peripheral T-cell lymphoma (PTCL). This study… read more here.
Keywords: allo hsct; study; auto hsct; cell ... See more keywords
The impact of pulmonary function in patients undergoing autologous stem cell transplantation.
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DOI: 10.1182/bloodadvances.2021004863
Abstract: High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-HSCT) is an established therapy for patients with hematological malignancies. The age of patients undergoing auto-HSCT, and therefore the co-morbidities, has increased during the last decades.… read more here.
Keywords: high dose; dose melphalan; auto hsct; patients undergoing ... See more keywords
Impact of Second Primary Malignancy Post-Autologous Transplantation on Outcomes of Multiple Myeloma: A CIBMTR Analysis.
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DOI: 10.1182/bloodadvances.2022009138
Abstract: The overall survival (OS) has improved significantly in multiple myeloma (MM) over the last decade with use of proteasome inhibitor and immunomodulatory drug-based combinations, followed by high-dose melphalan and autologous hematopoietic stem cell transplantation (auto-HSCT)… read more here.
Keywords: multiple myeloma; spm shm; second primary; auto hsct ... See more keywords
Increased circulating CD4+FOXP3+ T cells associate with early relapse following autologous hematopoietic stem cell transplantation in multiple myeloma patients
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DOI: 10.18632/oncotarget.25553
Abstract: We investigated dynamics of CD4+FOXP3+ T cell recovery following the high-dose chemotherapy (HDC) with autologous hematopoietic stem cell transplantation (auto-HSCT) in multiple myeloma (MM) patients. Circulating CD4+FOXP3+ T cells of 79 MM patients were evaluated… read more here.
Keywords: auto hsct; cd4 foxp3; circulating cd4; foxp3 cells ... See more keywords
Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study.
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DOI: 10.2169/internalmedicine.1314-22
Abstract: Objective High-dose chemotherapy with autologous hematopoietic stem cell transplantation (auto-HSCT) is an effective treatment option for relapsed and refractory aggressive malignant lymphoma. However, patients frequently experience treatment-induced gastrointestinal symptoms. Synbiotics, including live microorganisms and nondigestible… read more here.
Keywords: patients undergoing; auto hsct; placebo; group ... See more keywords
Efficacy of chimeric antigen receptor T cell therapy and autologous stem cell transplant in relapsed or refractory diffuse large B-cell lymphoma: A systematic review
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DOI: 10.3389/fimmu.2022.1041177
Abstract: Background We aimed to compare the efficacy of chimeric antigen receptor T (CAR-T) cell therapy with that of autologous stem cell transplantation (auto-HSCT) in relapsed/refractory diffuse large B cell lymphoma (R/R DLBCL). Research design and… read more here.
Keywords: car; cell; cell therapy; auto hsct ... See more keywords
Autologous hematopoietic stem cell transplantation for acute myeloid leukemia - single center experience.
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DOI: 10.4149/neo_2017_512
Abstract: We aimed to determine the effect of autologous hematopoietic stem cell transplantation (auto-HSCT) on acute myeloid leukemia (AML) patients as a valid alternative therapeutic option for patients without HLA-compatible donor. This retrospective single center study… read more here.
Keywords: auto; auto hsct; cell transplantation; autologous hematopoietic ... See more keywords