Pd-Catalyzed Rearrangement of N-Alloc-N-allyl Ynamides via Auto-Tandem Catalysis: Evidence for Reversible C-N Activation and Pd(0)-Accelerated Ketenimine Aza-Claisen Rearrangement.
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DOI: 10.1021/acs.orglett.0c04078
Abstract: An auto-tandem catalytic double allylic rearrangement of N-alloc-N-allyl ynamides was developed. This reaction proceeds through two separate and distinct catalytic cycles with both decarboxylative Pd-π-allyl and Pd(0)-promoted aza-Claisen rearrangements occurring. A detailed mechanistic study supported… read more here.
Keywords: auto tandem; aza claisen; alloc allyl; rearrangement ... See more keywords
Cascade Multicomponent Assemblies Involving 1,3-Enynes via Auto-Tandem Palladium Catalysis.
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DOI: 10.1021/acs.orglett.2c02544
Abstract: Here we report a three-component auto-tandem reaction of 1,3-enyne-tethered carbonyls, organoboronic reagents, and suitable nucleophiles catalyzed by palladium, proceeding through consecutive intramolecular vinylogous addition, Suzuki coupling, and allylic alkylation. This process exhibited high chemo- and… read more here.
Keywords: multicomponent assemblies; auto; palladium; auto tandem ... See more keywords
Auto-Tandem Catalytic Reductive Hydroformylation in a CO2-Switchable Solvent System
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DOI: 10.1021/acssuschemeng.2c00419
Abstract: Upgradation of olefin-enriched Fischer–Tropsch cuts by the synthesis of alcohols leads to drop-in-capable biosynthetic fuels with low carbon emissions. As an alternative to the conventional two-step production of long-chain alcohols, tandem catalytic systems improve the… read more here.
Keywords: system; tandem catalytic; switchable solvent; auto tandem ... See more keywords
Auto-Tandem Copper-Catalyzed Carboxylation of Undirected Alkenyl C-H Bonds with CO2 by Harnessing β-Hydride Elimination.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10754
Abstract: The exploration into challenging scenarios of the application of elementary reactions offers excellent opportunities for the development of unique transformations under organometallic catalysis. As a ubiquitous reaction of metal alkyl complexes, β-hydride elimination plays a… read more here.
Keywords: copper; carboxylation; hydride elimination; auto tandem ... See more keywords