COVID‐19 is associated with bystander polyclonal autoreactive B cell activation as reflected by a broad autoantibody production, but none is linked to disease severity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28134
Abstract: Coronavirus disease 2019 (COVID‐19) is associated with autoimmune features and autoantibody production in a small subset of the population. Pre‐existing neutralizing antitype I interferons (IFNs) autoantibodies are related to the severity of COVID‐19. Plasma levels… read more here.
Keywords: associated bystander; disease; autoantibody production; covid ... See more keywords
Autoantibody Production in Obesity: Is There Evidence for a Link Between Obesity and Autoimmunity?
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DOI: 10.1007/s13679-020-00397-8
Abstract: Purpose of Review During the last decades, obesity and autoimmune disorders have shown a parallel significant rise in industrialized countries. This review aims at providing a comprehensive update of the relationship between the adipose tissue… read more here.
Keywords: obesity; autoantibody production; autoimmune disorders;
Interrelation of Diet, Gut Microbiome, and Autoantibody Production
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DOI: 10.3389/fimmu.2018.00439
Abstract: B cells possess a predominant role in adaptive immune responses via antibody-dependent and -independent functions. The microbiome of the gastrointestinal tract is currently being intensively investigated due to its profound impact on various immune responses,… read more here.
Keywords: interrelation diet; autoantibody production; production; microbiome autoantibody ... See more keywords
IGF1R signalling is a guardian of self-tolerance restricting autoantibody production
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.958206
Abstract: Objective Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these areas. IGF1R is broadly expressed by antigen-presenting cells (APC). Using mice immunised with… read more here.
Keywords: apcs; autoantibody production; production; igf1r signalling ... See more keywords