Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis.
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DOI: 10.1021/acschembio.8b00668
Abstract: N-methylation of nucleic acids, proteins, and peptides is a chemical modification with significant impact on biological regulation. Despite the simplicity of the structural change, N-methylation can influence diverse functions including epigenetics, protein complex formation, and… read more here.
Keywords: methylation; autocatalytic backbone; molecular basis; backbone methylation ... See more keywords