Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis
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DOI: 10.1093/nar/gky183
Abstract: Abstract Haploid mouse embryonic stem cells (ESCs), in which a single hit mutation is sufficient to produce loss-of-function phenotypes, have provided a powerful tool for forward genetic screening. This strategy, however, can be hampered by… read more here.
Keywords: mutagenesis; mouse embryonic; homozygous mutant; autodiploidization ... See more keywords