B cell modulation with anti-CD79bantibodies ameliorates experimental autoimmune encephalitis in mice.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of immunology"
DOI: 10.1002/eji.202149523
Abstract: B cells play a major role in the pathogenesis of many autoimmune diseases like multiple sclerosis, rheumatoid arthritis or systemic lupus erythematosus. Depletion of B cells with anti-CD20 antibodies is an established therapy for multiple… read more here.
Keywords: autoimmune encephalitis; cell modulation; experimental autoimmune; cell ... See more keywords
Targeting IL‐34 in inflammatory autoimmune diseases
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DOI: 10.1002/jcp.28946
Abstract: Interleukin‐34 (IL‐34) shares a common receptor with macrophage colony‐stimulating factor (M‐CSF), and can bind to CSF‐1R, induces lymphocytes differentiation, proliferation, and regulates the synthesis of inflammatory components. Recent findings reported aberrant expression of IL‐34 in… read more here.
Keywords: targeting inflammatory; autoimmune; autoimmune diseases; physiology ... See more keywords
Incidence of autoimmune diseases in patients with scabies: a nationwide population-based study in Taiwan
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology International"
DOI: 10.1007/s00296-017-3717-2
Abstract: Scabies is a commonly occurring infectious immune-mediated inflammatory skin disease. Immune-mediated inflammatory processes are also observed in autoimmune diseases. There have been very few previous studies; however, that have investigated the possible association between scabies… read more here.
Keywords: autoimmune; nationwide population; population based; autoimmune diseases ... See more keywords
Lung fibrosis in autoimmune diseases and hypersensitivity: how to separate these from idiopathic pulmonary fibrosis
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DOI: 10.1007/s00296-021-05002-2
Abstract: Lung involvement in autoimmune diseases (AID) is uncommon, but may precede other organ manifestations. A diagnostic problem is chronicity presenting with lung fibrosis. A new category of interstitial pneumonia with autoimmune features for patients with… read more here.
Keywords: autoimmune; fibrosis; etiology; aid ... See more keywords
Biomarkers and Pathogenic Mechanisms in Autoimmunity
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DOI: 10.1007/s12026-016-8864-0
Abstract: The overall frequency of all autoimmune diseases in the general population is estimated at 5–8 %. More importantly, there has been an alarming increase in incidence for autoimmune diseases in recent decades. All ages are… read more here.
Keywords: autoimmune; mechanisms autoimmunity; autoimmune diseases; pathogenic mechanisms ... See more keywords
Plasma alpha-L-fucosidase activity in chronic inflammation and autoimmune disorders in a pediatric cohort of hospitalized patients
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DOI: 10.1007/s12026-017-8943-x
Abstract: Human α-fucosidase (EC 3.2.1.51) is an enzyme (hydrolase) of particular biological and medical interest, as the inherited deficiency in its activity leads to fucosidosis, a pathology belonging to severe glycoprotein lysosomal storage disorders. Although its… read more here.
Keywords: plasma; autoimmune; fucosidase; pediatric cohort ... See more keywords
Autoimmune/inflammatory syndrome induced by adjuvants—ASIA—related to biomaterials: analysis of 45 cases and comprehensive review of the literature
Sign Up to like & getrecommendations! Published in 2018 at "Immunologic Research"
DOI: 10.1007/s12026-017-8980-5
Abstract: Systemic autoimmune or granulomatous disorders related to biomaterials of human use have rarely been described. The aim of this study was to report cases of autoimmune/inflammatory syndrome induced by adjuvants (ASIA) related to biomaterial injections… read more here.
Keywords: autoimmune; syndrome induced; related biomaterials; inflammatory syndrome ... See more keywords
Autoimmune liver disease-associated serologic profiling in Chinese patients with acute hepatitis E virus infection
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DOI: 10.1007/s12026-021-09178-4
Abstract: The association between hepatitis E virus (HEV) and autoimmune liver diseases has been well-researched; however, the focus has been on autoimmune hepatitis (AIH) and not primary biliary cholangitis (PBC). Therefore, we aimed to investigate the… read more here.
Keywords: autoimmune; hepatitis; pbc; infection ... See more keywords
Translocator Protein Ligand PIGA1138 Reduces Disease Symptoms and Severity in Experimental Autoimmune Encephalomyelitis Model of Primary Progressive Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Neurobiology"
DOI: 10.1007/s12035-022-02737-2
Abstract: Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous system (CNS) caused by CNS infiltration of peripheral immune cells, immune-mediated attack of the myelin sheath, neuroinflammation, and/or axonal/neuronal dysfunctions. Some drugs… read more here.
Keywords: multiple sclerosis; eae; mog eae; protein ... See more keywords
T Lymphocytes and Autoimmunity.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2018.05.008
Abstract: T lymphocytes play a central role in regulation of the immune system. Both effector and regulatory T cells work in equilibrium to provide optimal immune response against foreign pathogens. Normally, T cells do not react… read more here.
Keywords: autoimmune; lymphocytes autoimmunity; biology; role ... See more keywords
IgA deficiency and autoimmune comorbidities in Juvenile Idiopathic Arthritis.
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DOI: 10.1016/j.anpede.2022.03.004
Abstract: OBJECTIVES (1) To describe the prevalence of IgA deficiency (IgAD), uveitis, coeliac disease (CD) and thyroid disorders in a multicentric cohort of patients diagnosed with JIA and, (2) to evaluate whether patients with JIA and… read more here.
Keywords: autoimmune; iga deficiency; iga; autoimmune comorbidities ... See more keywords