Impact of obesity on autoimmune arthritis and its cardiovascular complications.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.02.007
Abstract: Obesity can instigate and sustain a systemic low-grade inflammatory environment that can amplify autoimmune disorders and their associated comorbidities. Metabolic changes and inflammatory factors produced by the adipose tissue have been reported to aggravate autoimmunity… read more here.
Keywords: autoimmune arthritis; impact obesity; obesity; arthritis ... See more keywords
Immune checkpoint inhibitor–induced inflammatory arthritis as a model of autoimmune arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12832
Abstract: The development of inflammatory arthritis in patients receiving immune checkpoint inhibitor therapy is increasingly recognized due to the growing use of these drugs for the treatment of cancer. This represents an important opportunity not only… read more here.
Keywords: immune checkpoint; autoimmune arthritis; development; arthritis ... See more keywords
SAT0039 ZAP-70 CONTROLS AUTOIMMUNE ARTHRITIS VIA REGULATION OF APOPTOSIS THROUGH BCL-2, BIM AND CBL IN T CELLS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6910
Abstract: Background: The recombinant human G1(rhG1)-induced mouse arthritis (GIA) model resembles human rheumatoid arthritis in many aspects1. Similarly, to RA, GIA is also a T cell dependent disease: T cell activation and apoptosis has been shown… read more here.
Keywords: arthritis; apoptosis; autoimmune arthritis; mice ... See more keywords
AB0292 EFFICACY AND SAFETY OF TWO BIOSIMILAR ETANERCEPT AFTER THE SWITCH FROM THEIR CORRESPONDING ORIGINATOR IN THE TREATMENT OF PATIENTS WITH AUTOIMMUNE ARTHRITIS; A RETROSPECTIVE ANALYSIS IN A REAL LIFE SETTING
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.2364
Abstract: The available biosimilars of etanercept are as effective and well tolerated as their bio originator molecule in the naive treatment of chronic autoimmune arthritis. More data about the switching from the bio originator are needed.To… read more here.
Keywords: none declared; treatment; autoimmune arthritis; rate ... See more keywords
Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretion
Sign Up to like & getrecommendations! Published in 2017 at "RMD Open"
DOI: 10.1136/rmdopen-2017-000436
Abstract: Objective Tumour necrosis factor alpha (TNF-α) plays an important role in rheumatoid arthritis (RA). TNF-α is synthesised as a membrane-anchored precursor and is fully activated by a disintegrin and metalloproteinase 17 (ADAM17)-mediated ectodomain shedding. Nardilysin… read more here.
Keywords: autoimmune arthritis; factor alpha; tumour necrosis; arthritis ... See more keywords
Extracellular histones aggravate autoimmune arthritis by lytic cell death
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.961197
Abstract: Although recent studies have demonstrated a proinflammatory effect of extracellular histones in sepsis via endothelial cytotoxicity, little is known about their contribution to autoimmune arthritis. Therefore, we investigated the role of extracellular histones in autoimmune… read more here.
Keywords: cytotoxicity; lytic cell; arthritis; extracellular histones ... See more keywords
Role of Citrullinated Collagen in Autoimmune Arthritis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179833
Abstract: Citrullination of proteins plays an important role in protein function and it has recently become clear that citrullinated proteins play a role in immune responses. In this study we examined how citrullinated collagen, an extracellular… read more here.
Keywords: citrullinated collagen; role; autoimmune arthritis; arthritis ... See more keywords