Innate immunity in latent autoimmune diabetes in adults.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes/metabolism research and reviews"
DOI: 10.1002/dmrr.3480
Abstract: Latent autoimmune diabetes in adults (LADA) is an autoimmune disease that shares some genetic, immunological and clinical features with both type 1 diabetes and type 2 diabetes. Immune cells including CD4+ T cells, CD8+ T… read more here.
Keywords: immunity; diabetes adults; autoimmune diabetes; type diabetes ... See more keywords
Pathophysiological characteristics in patients with latent autoimmune diabetes in adults using clamp tests: evidence of a continuous disease spectrum of diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Acta Diabetologica"
DOI: 10.1007/s00592-019-01387-6
Abstract: This study aimed to assess islet insulin secretion and insulin resistance in Chinese patients with latent autoimmune diabetes in adults (LADA). Twelve patients with LADA, 10 with type 1 diabetes mellitus (T1DM), 10 with type… read more here.
Keywords: patients latent; insulin; insulin secretion; autoimmune diabetes ... See more keywords
Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109447
Abstract: Mitochondria are principal metabolic organelles that are increasingly unveiled as immune regulators. However, it is currently not known whether mitochondrial-encoded peptides modulate T cells to induce changes in phenotype and function. In this study, we found… read more here.
Keywords: mitochondrial encoded; islet; destruction; autoimmune diabetes ... See more keywords
Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.06.012
Abstract: The gut microbiota is essential for the normal function of the gut immune system, and microbiota alterations are associated with autoimmune disorders. However, how the gut microbiota prevents autoimmunity in distant organs remains poorly defined.… read more here.
Keywords: endocrine cells; expression; gut microbiota; autoimmune diabetes ... See more keywords
Short-term safety profile of Sars-Cov2 vaccination on glucose control: Continuous glucose monitoring data in people with autoimmune diabetes
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes Research and Clinical Practice"
DOI: 10.1016/j.diabres.2021.109022
Abstract: In patients with autoimmune diabetes no significant differences were observed in glucose control, expressed as time in range evaluated by continuous glucose monitoring comparing the 3 days after Sars-Cov2 vaccine with the 14 days preceding… read more here.
Keywords: autoimmune diabetes; sars cov2; glucose control; glucose monitoring ... See more keywords
Combination of vitamin D and dipeptidyl peptidase-4 inhibitors (VIDPP-4i) as an immunomodulation therapy for autoimmune diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107518
Abstract: Type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA) represent the most common types of autoimmune diabetes and are characterized by different age of onset, degrees of immune-mediated destruction of pancreatic beta cells… read more here.
Keywords: autoimmune; dipeptidyl peptidase; inhibitors vidpp; autoimmune diabetes ... See more keywords
Adult-onset autoimmune diabetes in 2020: An update.
Sign Up to like & getrecommendations! Published in 2020 at "Maturitas"
DOI: 10.1016/j.maturitas.2020.04.014
Abstract: An increasing number of new cases of autoimmune diabetes occur during adulthood. Most are cases of latent autoimmune diabetes in adults (LADA), a form of autoimmune diabetes with older mean age at onset, slower rate… read more here.
Keywords: adult onset; autoimmune; 2020 update; diabetes 2020 ... See more keywords
Development of the Nonobese Diabetic Mouse and Contribution of Animal Models for Understanding Type 1 Diabetes
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DOI: 10.1097/mpa.0000000000000828
Abstract: Abstract In 1974, the discovery of a mouse and a rat that spontaneously developed hyperglycemia led to the development of 2 autoimmune diabetes models: nonobese diabetic (NOD) mouse and Bio-Breeding rat. These models have contributed… read more here.
Keywords: autoimmune diabetes; type diabetes; nonobese diabetic; development ... See more keywords
Use of Swedish smokeless tobacco (snus) and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA)
Sign Up to like & getrecommendations! Published in 2017 at "Diabetic Medicine"
DOI: 10.1111/dme.13179
Abstract: It has been suggested that moist snuff (snus), a smokeless tobacco product that is high in nicotine and widespread in Scandinavia, increases the risk of Type 2 diabetes. Previous studies are however few, contradictory and,… read more here.
Keywords: risk type; type diabetes; snus; autoimmune diabetes ... See more keywords
Long‐term risk of cardiovascular disease in individuals with latent autoimmune diabetes in adults (UKPDS 85)
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DOI: 10.1111/dom.13788
Abstract: Latent autoimmune diabetes in adults (LADA) is diagnosed in up to 12% of adults with clinically diagnosed type 2 diabetes (T2D). LADA tends to have healthier cardiovascular (CV) risk profiles than T2D, but it remains… read more here.
Keywords: risk; diabetes adults; long term; autoimmune diabetes ... See more keywords
A juvenile case with the coexistence of MODY1 and later-onset latent autoimmune diabetes in youth (LADY).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of diabetes investigation"
DOI: 10.1111/jdi.13215
Abstract: We present the case of a 12-year-old Japanese girl, who was positive for markers of both, maturity onset diabetes of the young (MODY) and latent autoimmune diabetes in youth (LADY). She was initially diagnosed with… read more here.
Keywords: youth lady; autoimmune diabetes; case; diabetes youth ... See more keywords