Articles with "autoimmune disorders" as a keyword



The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study

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Published in 2023 at "Epilepsia Open"

DOI: 10.1002/epi4.12727

Abstract: We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin‐dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)] and temporal lobe epilepsy (TLE),… read more here.

Keywords: temporal lobe; autoimmune disorders; systemic autoimmune; lobe epilepsy ... See more keywords

Zika and Dengue Virus Autoimmunity: An Overview of Related Disorders and Their Potential Mechanisms

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Published in 2025 at "Reviews in Medical Virology"

DOI: 10.1002/rmv.70014

Abstract: Zika virus (ZIKV) and dengue virus (DENV) are two major mosquito‐borne flaviviruses that pose a significant threat to the global public health system, particularly in tropical regions. The clinical outcomes related to these viral pathogens… read more here.

Keywords: virus; dengue virus; autoimmune disorders; zikv denv ... See more keywords
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Autoantibody Production in Obesity: Is There Evidence for a Link Between Obesity and Autoimmunity?

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Published in 2020 at "Current Obesity Reports"

DOI: 10.1007/s13679-020-00397-8

Abstract: Purpose of Review During the last decades, obesity and autoimmune disorders have shown a parallel significant rise in industrialized countries. This review aims at providing a comprehensive update of the relationship between the adipose tissue… read more here.

Keywords: obesity; autoantibody production; autoimmune disorders;

The association of other autoimmune diseases in patients with Graves' disease (with or without ophthalmopathy): Review of the literature and report of a large series.

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Published in 2019 at "Autoimmunity reviews"

DOI: 10.1016/j.autrev.2018.10.001

Abstract: Graves' disease (GD) and autoimmune thyroiditis (AT) are the two main clinical presentations of AITD, and their clinical hallmarks are thyrotoxicosis and hypothyroidism, respectively. GD, and AT, can be associated with other organ specific, or… read more here.

Keywords: autoimmune; autoimmune diseases; autoimmune disorders; association autoimmune ... See more keywords
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Interaction between food antigens and the immune system: Association with autoimmune disorders.

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Published in 2020 at "Autoimmunity reviews"

DOI: 10.1016/j.autrev.2020.102459

Abstract: It has been shown that environmental factors such as infections, chemicals, and diet play a major role in autoimmune diseases; however, relatively little attention has been given to food components as the most prevalent modifiers… read more here.

Keywords: autoimmune disorders; tissue; food antigens; food proteins ... See more keywords
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The Yin and Yang of myelodysplastic syndromes and autoimmunity: The paradox of autoimmune disorders responding to therapies specific for MDS.

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Published in 2019 at "Critical reviews in oncology/hematology"

DOI: 10.1016/j.critrevonc.2019.07.018

Abstract: The biological milieu and clinical picture of myelodysplastic syndromes (MDS) is characterised by a variety of immune mechanisms and manifestations, including an increased frequency of autoimmune disorders. The present review will try to shed some… read more here.

Keywords: syndromes autoimmunity; myelodysplastic syndromes; yang myelodysplastic; yin yang ... See more keywords
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Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials.

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Published in 2017 at "Human immunology"

DOI: 10.1016/j.humimm.2016.12.010

Abstract: Naïve CD4+ T cells are pleiotropically divided into various T helper (Th) cell subsets, according to their pivotal roles in the regulation of immune responses. The differentiation of Th9 cells, an interleukin (IL)-9 producing subset,… read more here.

Keywords: disorders pathogenesis; th9 cells; autoimmune disorders; therapeutic potentials ... See more keywords

Mechanistic basis of co-stimulatory CD40-CD40L ligation mediated regulation of immune responses in cancer and autoimmune disorders.

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Published in 2019 at "Immunobiology"

DOI: 10.1016/j.imbio.2019.151899

Abstract: Generation of an accurate humoral and a cell mediated adaptive immune responsesare dictated by binding of an antigen to a T- and a B-cell receptor, respectively (first signal) followed by ligation of costimulatory molecules (second… read more here.

Keywords: immune; cd40 cd40l; cancer autoimmune; autoimmune disorders ... See more keywords

Associations of pemphigus or pemphigoid with autoimmune disorders in US adult inpatients.

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Published in 2019 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2019.07.029

Abstract: BACKGROUND Few large-scale and controlled studies examined the associations and predictors of the gamut of autoimmune conditions in pemphigus and pemphigoid. OBJECTIVE To examine associations of pemphigus or pemphigoid with autoimmune disorders and related outcomes… read more here.

Keywords: pemphigus pemphigoid; autoimmune disorders; pemphigoid autoimmune; disorders adult ... See more keywords

Novel Imidazotriazine Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Disorders.

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Published in 2023 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.3c00139

Abstract: Provided herein are novel imidazotriazine derivatives used as IL-17 modulators, their pharmaceutical compositions, the use of such compounds in treating inflammatory and autoimmune disorders, and processes for preparing such compounds. read more here.

Keywords: inflammatory autoimmune; treating inflammatory; novel imidazotriazine; imidazotriazine derivatives ... See more keywords

Identification of Causal Effects of Mitochondrial Dysfunction on the Risk of Multiple Autoimmune Disorders: Multi‐Omics Mendelian Randomization and Colocalization Analyses

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Published in 2025 at "International Journal of Rheumatic Diseases"

DOI: 10.1111/1756-185x.70383

Abstract: Mitochondrial dysfunction has been implicated in the pathogenesis of autoimmune disorders (AIDs), but its causal role in disease susceptibility and progression remains unclear. This study explores potential causal associations between mitochondrial‐related genes and AIDs using… read more here.

Keywords: colocalization analyses; multi omics; autoimmune disorders; mitochondrial dysfunction ... See more keywords