Metabolic reprogramming orchestrates CD4+ T-cell immunological status and restores cardiac dysfunction in autoimmune induced-dilated cardiomyopathy mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.08.002
Abstract: Cellular autoimmune responses, especially those mediated by T-cells, play vital roles in the immunopathogenesis of dilated cardiomyopathy (DCM). Metabolic reprogramming directly controls T-cell function, imprinting distinct functional fates. However, its contribution to T-cell dysfunction and… read more here.
Keywords: cell dysfunction; metabolic reprogramming; autoimmune induced; dysfunction ... See more keywords
AUTOIMMUNE INDUCED HEART BLOCK
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)33152-8
Abstract: Rheumatoid arthritis (RA) is a very common autoimmune disease, affecting around 1% of the general population. Although not always clinically apparent, it can manifest in the form of cardiovascular pathology in 50% of affected patients(1).… read more here.
Keywords: cardiology; autoimmune induced; pathology; induced heart ... See more keywords